From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 117685 10.52957/2782-1900-2026-7-1-43-53 Научные статьи Scientific articles Научные статьи Sintez 2,4,7,9-tetrafenil-4,4a,9,9a-tetragidrotiopirano[2,3-g]tiokhromen-5,10(5aH,10aH)-diona i analiz ego biologicheskoi aktivnosti Синтез 2,4,7,9-тетрафенил-4,4a,9,9a-тетрагидротиопирано[2,3-g]тиохромен-5,10(5aH,10aH)-диона и анализ его биологической активности Немиров Даниил Михайлович Nemirov Daniil Mihaylovich dmnemirov@bk.ru Овчинников Константин Львович Ovchinnikov Konstantin L'vovich

кандидат химических наук;

candidate of chemical sciences;

 Ярославский государственный технический университет Yaroslavl State Technical University 24 03 2026 24 03 2026 7 1 43 53 29 01 2026 16 03 2026 https://ystu.editorum.ru/en/nauka/article/117685/view

Синтезирован 2,4,7,9-тетрафенил-4,4a,9,9a-тетрагидро-тиопирано[2,3-g]тиохромен-5,10(5aH,10aH)-дион. Проведен его молекулярный докинг с рецептором GABAB(1), рассчитана его аффинность и токсичность. Выполнены компьютерные расчеты с использованием программы PASS-Online с целью выявления биологических активностей.

Синтезирован 2,4,7,9-тетрафенил-4,4a,9,9a-тетрагидро-тиопирано[2,3-g]тиохромен-5,10(5aH,10aH)-дион. Проведен его молекулярный докинг с рецептором GABAB(1), рассчитана его аффинность и токсичность. Выполнены компьютерные расчеты с использованием программы PASS-Online с целью выявления биологических активностей.

 2Н-тиопираны молекулярный докинг гетеро-реакция Дильса-Альдера рецептор GABAB(1) аффинность токсичность PASS-Online

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